Dandruff is the shedding of dead skin cells from the scalp. As skin cells die a small amount of flaking is normal; about 487,000 cells/cm2 get released normally after detergent treatment. Some people, however, experience an unusually large amount of flaking either chronically or as a result of certain triggers, up to 800,000 cells/cm2, which can also be accompanied by redness and irritation.
Dandruff is a common scalp disorder affecting almost half of the population at the post-pubertal age and of any gender and ethnicity. It often causes itching. It has been well established that keratinocytes play a key role in the expression and generation of immunological reactions during dandruff formation. The severity of dandruff may fluctuate with season as it often worsens in winter. Most cases of dandruff can be easily treated with specialized shampoos. There is, however, no true cure.
Those affected by dandruff find that it can cause social or self-esteem problems, indicating treatment for both psychological and physiological reasons.
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